Read e-book online Discovering biomolecular mechanisms with computational PDF

By Frank Eisenhaber

This anthology provides serious studies of equipment and high-impact purposes in computational biology that result in effects that non-bioinformaticians should also understand to layout effective experimental learn plans. studying Biomolecular Mechanisms with Computational Biology explores the method of translating series strings into organic wisdom and considers exemplary groundbreaking effects equivalent to unforeseen enzyme discoveries. This e-book additionally summarizes non-trivial theoretical predictions for regulatory and metabolic networks that experience bought experimental confirmation.

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A gene coexpression network for global discovery of conserved genetic modules. Science 2003; 302:249-255. 78. Ito T, Chiba T, Ozawa R et al. A comprehensive two-hybrid analysis to explore the yeast protein interactome. Proc N a d Acad Sci USA 2 0 0 1 ; 98:4569-4574. 79. Krogan NJ, Peng W T , Cagncy G et al. High-definition macromolecular composition of yeast RNA-processing complexes. Mol Cell 2004; 13:225-239. 80. Valasek L, Hasek J, Nielsen KH et al. Dual function of e I F 3 j / H c r l p in processing 20 S prerRNA and translation initiation.

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