Get Biology of the Lymphokines PDF

By Stanley Cohen

Show description

Read or Download Biology of the Lymphokines PDF

Similar biology books

New PDF release: The Biology of Seeds: Recent Research Advances

This ebook offers edited and revised papers from the 7th foreign Workshop on Seeds, held in Salamanca, Spain, in may perhaps 2002. the foremost subject matters addressed contain seed improvement, germination and dormancy, in addition to desiccation, seed ecology and seed biotechnology.

Download e-book for iPad: Root Hairs: Cell and Molecular Biology by Moira E. Galway (auth.), Robert William Ridge, Anne Mie C.

Root hairs are tip-growing cells that originate from epidennal cells referred to as trichoblasts. Their function might be easily considered extending the outside quarter of the foundation to facilitate absorption of foodstuff and water. even though, as you will discover during this publication, the foundation hair is way greater than that. To an more and more higher variety of plant biologists, the basis hair is a version mobile.

F. F. Nord's Advances in Enzymology and Related Areas of Molecular PDF

Advances in Enzymology and similar components of Molecular Biology is a seminal sequence within the box of biochemistry, delivering researchers entry to authoritative stories of the newest discoveries in all components of enzymology and molecular biology. those landmark volumes date again to 1941, offering an unmatched view of the historic improvement of enzymology.

Additional resources for Biology of the Lymphokines

Sample text

Very little information is available on lymphokines with chemotactic activities for neutrophils (Altman, 1978). Ward et al. (1970) described a soluble factor found in antigen-stimulated guinea pig lym­ phocyte cultures that attracts neutrophils in the Boyden double chamber assay and is distinct from MCF and MIF. T h e potency of this factor is considerably less than the MCF potency described in the same system and this may possibly explain the paucity of neutrophils relative to mononuclear cells in some delayed hypersensitivity reactions.

Andreis and co-workers (1974) reported that P P 2. LYMPHOKINES AS INFLAMMATORY MEDIATORS 43 chronic synovitis could be induced in rabbits following three intraarticu­ lar injections of concentrated MIF-containing supernatants. T h e result­ ing synovitis was characterized by synovial effusion, hyperplasia of the lining layer, and infiltration of the sublining layers with mononuclear cells and some fibroblasts. Injection of the concentrated control super­ natant into the contralateral joint did not result in inflammation.

V. injection of an antigen bolus. , the one receiving the high dose of antigen, showed no skin reactivity to antigen nor were there lymphocytes capable of producing MIF in vitro. v. with saline) demonstrated no serum MIF but manifested cutaneous de­ layed hypersensitivity to the antigen and their lymphocytes exhibited significant MIF production in vitro. T h e serum MIF in the desensitized animals was a transient response, since they demonstrated the same reactivity as the controls 7 days after antigen challenge.

Download PDF sample

Rated 4.24 of 5 – based on 45 votes