By Polina Prokopovich
Biological and Pharmaceutical purposes of Nanomaterials provides the findings of state of the art examine actions within the box of nanomaterials, with a selected emphasis on organic and pharmaceutical functions. Divided into 4 sections―nanomaterials for drug supply, antimicrobial nanomaterials, nanomaterials in biosensors, and security of nanomaterials―this book:
- Covers themes resembling stimuli-responsive nanostructured silica matrixes, gold nanoparticles, and liposomes for focusing on drug supply and dental applications
- Describes using nanocarriers and nanoparticles as melanoma and peptide therapeutics, the impression of floor features on microbial adhesion, and the most recent advancements in antimicrobial nanostructured polymers for scientific applications
- Discusses contemporary advances in nanodiagnostic thoughts for infectious brokers, chromogenic biosensors for pathogen detection, electrochemical biosensors for detecting DNA harm and genotoxicity, and molecular imaging with quantum dots together with floor ameliorations by means of polymers for biosensing applications
Featuring contributions from box specialists and researchers in and academia, Biological and Pharmaceutical functions of Nanomaterials provides state of the art info on nanomaterials and their use in drug supply, an infection keep watch over, and biomedicine.
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Additional resources for Biological and pharmaceutical applications of nanomaterials
Control. Release, 128, 157–164 (2008). 91. Q. Yang, S. Wang, P. Fan, L. Wang, Y. Di, K. -S. Xiao, pH-Responsive Carrier System Based on Carboxylic Acid Modified Mesoporous Silica and Polyelectrolyte for Drug Delivery, Chem. , 17, 5999–6003 (2005). 92. J. Kecht, and T. Bein, Functionalization of Colloidal Mesoporous Silica by Metalorganic Reagents, Langmuir, 24, 14209–14214 (2009). A. Schlossbauer, J. Kecht, and T. Bein, Biotin–Avidin as a Protease-Responsive Cap System for Controlled Guest Release from Colloidal Mesoporous Silica, Angew.
However, without inner surface modification of mesoporous silica, only weak hydrogen bonding involving the silanol group could be expected. Thus, the guest drug molecule should contain a hydrogen bonding group to improve drug loading efficiency. 91 Among some outstanding results, Balas et al. 119 Alendronate is a bisphosphonate, used as a model drug in osteoporosis treatment. 4 where electrostatic interaction between the guest molecule and the host mesoporous silica becomes too weak. Metal-involved coordination bonding–based mesoporous silica is also a good approach for pH-responsive DDS.
Chem. , 125, 4451–4459. 4 Light-Responsive MSN Photoactive silica materials also became very useful in the control of drug delivery through organic light stimuli–sensitive molecules. Generally, they are grafted at the pore outlets and act as gatekeepers. In such systems, the drug delivery is activated by external light and usually drug molecules do not have a light absorption band overlapped with the gatekeeper molecules in order to follow the release efficiency. In this context, Fujiwara et al.