Download e-book for kindle: Biochemical Protozoology As A Basis For Drug Design by ichael J.North, Graham H. Coombs

By ichael J.North, Graham H. Coombs

A compilation of articles on protozoological biochemistry which stories the topic zone and gives info on present examine. integrated within the issues lined Are strength Metabolism Of Anaerobic Parasitic Protists, proteinases of African

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M. , 1989, Red cell membrane protein distribution during malarial invasion, Journal of Cell Science, 92, 691–9. , Tappendem, L. , 1979, Synthesis of Plasmodium knowlesi polypeptides in a cell free system, Bulletin of the World Health Organization, 57, 109–12. , Tovey, G. , 1985, The chemotherapy of rodent malaria, XXXIX ultrastructural changes following treatment with artemisinine of Plasmodium berghei infection in mice, with observations of the localization of 3H-dihydroartemisinine in P. falciparum in vitro.

Feder, R. , 1983, In vitro, biosynthesis and core gylcosylation of the histidinerich protein Plasmodium lophurae. Molecular and Biochemical Parasitology, 9, 351–62. , 1989, Ferriprotoporphyrin IX: role in chloroquine susceptibility and resistance in malaria, in Malaria and the Red Cell, Vol. 2, pp. Liss. D. , 1987, The state of ferriprotoporphyrin IX in malaria pigment. Journal of Biological Chemistry, 262, 15552–5. A. , 1972, The metabolism of the malaria parasite and its host, Advances in Parasitology, 10, 31–48.

1983); however, the isolated digestive vacuoles of P. e. , 1990). , 1990; and see Chapter 24). Serine and metalloproteases were also in evidence and it was claimed that these function after aspartic protease action. In many respects, these results with P. falciparum confirm the report of cathepsin D (an aspartic protease) in P. lophurae (Sherman and Tanigoshi, 1983). Other reviews on the proteinases of Plasmodium are given elsewhere in this volume (Chapters 24 and 25). It would be of considerable interest to localize, at the ultrastructure level, the various proteinases in the P.

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